We describe a rare case of a 34-year-old woman who presented with progressive, destructive midline facial lesions initially concerning for chronic rhinofacial mucormycosis. However, subsequent tissue biopsy and pathologic evaluation established the diagnosis of extranodal NK/T-cell lymphoma. The patient demonstrated rapid disease progression despite prompt initiation of asparaginase-based chemotherapy, highlighting the diagnostic challenges and aggressive course of this malignancy that may resemble invasive fungal infection.
Yun et al. (Tue,) studied this question.