Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti‐inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies

Key Points

• To evaluate the analgesic, anti-inflammatory, and thrombolytic effects of Adenostemma lavenia acetone extract.
• Conducted in vivo and in vitro experiments in Swiss Albino mice
• Utilized molecular docking and density functional theory for computational analysis
• Isolated phytoconstituents for further evaluation
• Adenostemma lavenia acetone extract demonstrated significant analgesic activity
• Exhibited strong anti-inflammatory properties
• Showed thrombolytic effects, particularly associated with sesquiphellandrene

Abstract