389例非血缘关系肥厚型心肌病患者中β-肌球蛋白重链基因的综合分析

Driest等人（Sun,）在肥厚型心肌病（n=389）中进行了一项观察性研究。比较了MYH7突变组与无MYH7突变组的诊断年龄（岁）（p=0.0002）。携带MYH7突变的HCM患者诊断年龄较轻（32.9岁 vs. 42.7岁，p=0.0002），肥厚更明显，但直系亲属中猝死频率无增高。

www.synapsesocial.com/papers/69f31e80b24eb58ef2fb05ac — DOI: https://doi.org/10.1016/j.jacc.2004.04.039

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