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免疫疗法被认为是癌症最有前景的治疗方法。多种癌症免疫疗法,包括细胞免疫治疗、肿瘤疫苗、抗体、免疫检查点抑制剂和小分子抑制剂,已取得一定成功。在本综述中,我们总结了巨噬细胞在当前免疫疗法中的作用及其靶向优势。为更好地理解和利用该类细胞,综述开篇整理了其发育与分化特征、类别、典型标志物及功能。基于或联合巨噬细胞的治疗策略有望提升癌症治疗的疗效。
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Zhaojun Duan
Yunping Luo
Signal Transduction and Targeted Therapy
Chinese Academy of Medical Sciences & Peking Union Medical College
Peking Union Medical College Hospital
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Duan 等人(周五)研究了这个问题。
www.synapsesocial.com/papers/6a06adec6b3d0007075828ee — DOI: https://doi.org/10.1038/s41392-021-00506-6