Systematic review and meta-analysis show e-cigarette taxation affects usage and pricing, indicating varied public health outcomes.
Cross-sectional analysis shows state e-cigarette flavor bans reduced young adult initiation by over 50%, indicating a need for broader public health strategies.
Cross-sectional study reveals e-cigarette use leads to oral health complications, indicating need for public health interventions.
Literature review reveals vaping prompts inflammatory changes and worsens clinical attachment loss in periodontitis.
Systematic review reveals varenicline effectively aids e-cigarette cessation, suggesting nicotine replacement therapy insufficient.
Formative evaluation reveals health communications effectively address dual use in LGBTQ+ young adults, highlighting risk perceptions and reactance.
Prospective study identifies key cardiometabolic risk factors in individuals with coronary artery disease, indicating a need for targeted prevention strategies.
Prospective study finds high prevalence of hypertension and diabetes among individuals with coronary artery disease, suggesting urgent need for intervention.
The use of electronic nicotine delivery systems (ENDS) is increasing rapidly across Sub-Saharan Africa (SSA), particularly among young women, while endometriosis remains substantially underdiagnosed in the region. Emerging evidence suggests that vaping may influence hormonal, inflammatory, and oxidative pathways relevant to endometriosis. This scoping review followed PRISMA guidelines and searched PubMed, Web of Science, Scopus, African regional databases, and grey literature to identify studies examining vaping exposure in relation to reproductive or hormonal outcomes and gynecologic pathology. Eligible studies were appraised using the Newcastle–Ottawa Scale and STROBE criteria, and findings were narratively synthesized due to methodological heterogeneity. Across epidemiologic and mechanistic domains, the evidence indicates that nicotine-product use is associated with higher odds of dysmenorrhea and suspected endometriosis; disrupts the hypothalamic–pituitary–gonadal axis and estrogen–progesterone signaling; induces oxidative stress, mitochondrial dysfunction, and NF-κB activation; and may drive epigenetic and immune alterations that promote endometrial adhesion, angiogenesis, and impaired fertility. Contextual vulnerabilities in SSA including environmental co-exposures, infectious disease burden, limited diagnostic capacity, and dual use of vaping with alcohol may further amplify these risks. Although direct causal data from SSA remain limited, the convergence of biological plausibility and emerging epidemiologic signals highlights vaping as a potential reproductive health concern, underscoring the need to integrate vaping into sexual and reproductive health guidelines and to prioritize region-specific research.
Abstract Background and aims Smokers quitting successfully with the help of e‐cigarettes often continue vaping. It is not known whether this promotes or prevents relapse back to smoking. This study aimed to determine whether use of e‐cigarettes after successful smoking cessation affects the probability of relapse later on. Design Secondary analysis of a randomised controlled trial where participants received combination nicotine replacement therapy (NRT) or e‐cigarettes to compare relapse rates in the two study arms and in abstainers who did and did not use e‐cigarettes. Setting Four stop‐smoking services in the United Kingdom. Participants 886 smokers (median age 41, smoking on average 15 cigarettes per day, 48% female) seeking help with stopping smoking. Measurements Main outcome was relapse to smoking by 12 months in participants who were abstinent at 4 weeks or at 6 months. Relapse was defined as abstinence at 4 weeks but not at one year or abstinence at 6 months but not at one year. Abstinence from smoking was defined as no smoking over the past 7 days. E‐cigarette use was defined as using e‐cigarettes at the time of abstinence on at least one day per week. Findings Abstainers in the e‐cigarette arm were less likely to relapse than abstainers in the NRT arm [relative risk (RR) = 0.78, 95% confidence interval (CI) = 0.64–0.96 for relapse between 4 weeks and 1 year; RR = 0.71, 95% CI = 0.55–0.93 for relapse between 6 months and 1 year). Relapse rates over both time periods were also lower in abstainers who used e‐cigarettes compared with abstainers who did not use e‐cigarettes (RR = 0.79, 95% CI = 0.65–0.97 and RR = 0.75, 95% CI = 0.57–0.98, respectively). Conclusions Use of e‐cigarettes after stopping smoking is associated with a reduced risk of relapse.