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August 20, 2025Neuroradiology2 citationsOpen Access

Endovascular Therapy Compared to Medical Treatment for Intracranial Atherosclerotic Stenosis

Endovascular therapy vs. conventional medical treatment for symptomatic intracranial atherosclerotic stenosis: an updated meta-analysis of randomized controlled trials

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Authors

HSHusam Abu SuilikMBMohammed BakerANAhmed Naeem

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Overview

Systematic review reveals endovascular therapy increases risks of mortality and strokes in patients with intracranial atherosclerotic stenosis, suggesting caution in its use.

Key Points

  • Endovascular therapy significantly increased the risk of short-term mortality and stroke compared to conventional medical treatment.
  • Results showed an odds ratio of 3.19 for mortality or stroke with endovascular therapy and conventional medical treatment.
  • A systematic review and meta-analysis included five randomized controlled trials involving 1,531 patients with symptomatic intracranial atherosclerotic stenosis.
  • Endovascular therapy may not be beneficial as it raises the risk of hemorrhagic and ischemic strokes without improving long-term outcomes.

Cite This Study

Suilik et al. (2025) studied this question.

synapsesocial.com/papers/68af4eaead7bf08b1ead70edhttps://doi.org/10.1007/s00234-025-03736-5
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