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September 10, 2025The Indian Journal of Medical Research0 citationsOpen Access

Deprescribing & its associated factors among middle & old-aged ambulatory patients with chronic disease (s): A hospital-based cross-sectional study

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JLJia Hui LimIWIvy Mok Pooi WanTMTuan Mazlelaa Tuan Mahmood

Key Points

  • Willingness to deprescribe was reported by 83.2% of participants, suggesting high acceptance for medication reduction.
  • Key factors include patient involvement in treatment and trust in physicians, indicating collaborative care improves willingness.
  • Cross-sectional study utilized interviewer-assisted questionnaires among adults aged 40 and above in Malaysia's tertiary care.

Abstract

Background 95%confidence interval (CI): 1.02-1.32; P =0.02], appropriateness of deprescribing (OR: 1.17; 95% CI: 1.05-1.31; P =0.004), concerns about stopping medication (OR: 0.75; 95% CI: 0.67-0.83; P <0.001), and trust in physicians (OR: 1.26; 95% CI: 1.04-1.52; P =0.017) were found to be associated with the willingness towards deprescribing. Interpretation & conclusions The high prevalence (83.2%) of willingness to deprescribe among middle and old-age ambulatory patients demonstrates a promising opportunity for medication optimisation in Malaysian healthcare settings. The factors predicting their willingness to deprescribe were patients’ involvement in treatment, perceived appropriateness of deprescribing, medication cessation concern, and physician-patient trust relationships.

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Cite This Study

Lim et al. (2025) studied this question.

synapsesocial.com/papers/68c1c32e54b1d3bfb60f16a1https://doi.org/10.25259/ijmr_1747_2024
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lifestyle, chronic diseases and self-rated health among Malaysian adults: results from the 2011 National Health and Morbidity Survey (NHMS)2015 · 85 citations
  2. 2Quality of Life and Its Association With Treatment Satisfaction, Adherence to Medication, and Trust in Physician Among Patients With Hypertension2018 · 58 citations
  3. 3Development and validation of the patients’ attitudes towards deprescribing (PATD) questionnaire2012 · 109 citations
  4. 4ABC of Content Validation and Content Validity Index Calculation2019 · 2,045 citations
  5. 5A Meta‐Analysis of Research on Protection Motivation Theory2000 · 2,540 citations