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May 13, 2024Gut62 citationsOpen Access

Targeting squalene epoxidase restores anti-PD-1 efficacy in metabolic dysfunction-associated steatohepatitis-induced hepatocellular carcinoma

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JWJun WenXZXiang ZhangCWChi Chun Wong

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Abstract

Squalene epoxidase (SQLE) promotes metabolic dysfunction-associated steatohepatitis-associated hepatocellular carcinoma (MASH-HCC), but its role in modulating the tumour immune microenvironment in MASH-HCC remains unclear.

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Wen et al. (2024) studied this question.

synapsesocial.com/papers/68e6a4e8b6db6435876280afhttps://doi.org/10.1136/gutjnl-2023-331117
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