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October 8, 2025JCO Oncology Practice0 citations

Disparities in palliative care delivery for metastatic cancer patients: A nationwide analysis using the NIS 2020 dataset.

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AJAbdullah JamalWRWania RehmanMSMuhammad Talha Shaukat

Key Points

  • Only 25.5% of metastatic cancer patients received palliative care, indicating substantial accessibility issues.
  • Comparatively, patients receiving palliative care had a significantly higher in-hospital mortality of 31.3% versus 8.7% for non-recipients.
  • Logistic regression indicated that 'No charge' insurance significantly associated with higher odds of palliative care access.
  • System-level hurdles exist despite adjustments for demographics and hospital characteristics, suggesting a need for policy reform.

Abstract

114 Background: Palliative care plays a vital role in supporting patients with advanced cancer by focusing on comfort, communication, and quality of life. Despite its proven benefits, it is often introduced late in the course of illness, or not at all. Factors such as race, insurance type, and hospital characteristics may influence access, but these patterns are not fully understood. By examining national data, this study aims to identify who receives palliative care and when, helping to uncover disparities and improve end-of-life care delivery. Methods: We conducted a retrospective cross-sectional analysis using the 2020 National Inpatient Sample (NIS). Adult patients with metastatic cancer were identified using ICD-10 codes C77–C80, and we defined palliative care with code Z515. To compare demographics, outcomes, and hospital factors, we utilized chi-square tests, t-tests, and logistic regression. Our analysis included survey-weighted models that adjusted for the sampling design. We also conducted subgroup and interaction analyses to investigate how race, insurance, age, and hospital characteristics influenced the results. All statistical analyses were done on R software (Version 4.5.0). Results: In this national analysis of 4,098 metastatic cancer patients, 25.5% (n = 1,044) received palliative care. Compared to non-recipients (n = 3,054), those receiving palliative care had higher in-hospital mortality (31.3% vs. 8.7%, p 0.1). Survey-weighted models confirmed these findings. Interaction modeling showed no significant race–insurance interaction effect (p = 0.285). Teaching hospital status was significantly associated with increased palliative care delivery (OR = 1.17, p = 0.043). In patients aged ≥65 years (n = 1,988), no variables reached significance, though teaching hospitals again trended toward higher palliative use (p = 0.064). Proportional analysis revealed disparities in palliative care use across racial and insurance groups, despite adjustment. Conclusions: Palliative care was poorly accessed by patients with metastatic cancer, frequently initiated late despite high mortality. Insurance type, teaching hospital status, but not race or sex, influenced access. These results highlight system-level hurdles, and suggest the need for policies to facilitate the earlier integration of palliative care throughout all hospital environments.

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Cite This Study

Jamal et al. (2025) studied this question.

synapsesocial.com/papers/68e6f342f8145af55aeaccfchttps://doi.org/10.1200/op.2025.21.10_suppl.114
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