Retrospective cohort study shows SGRT enhances setup reproducibility in lung cancer treatment, indicating better outcomes.
Key Points
Evaluate the clinical benefits of surface-guided radiotherapy (SGRT) for enhancing setup precision in lung cancer particle therapy.
Retrospective cohort analysis of 63 lung cancer patients receiving 1277 treatment fractions.
Comparison of conventional laser-based positioning (983 fractions) with SGRT (294 fractions).
Manual registration of orthogonal images with digitally reconstructed radiographs to compute six degrees of freedom (6-DOF) correction parameters.
SGRT group showed significant median shifts reductions in lateral (0.25 cm to 0.21 cm, p = 0.021) and longitudinal (0.25 cm to 0.21 cm, p = 0.014) directions.
Pitch shifts decreased from 1.0° to 0.8° (p = 0.001), and three-dimensional vector magnitude improved from 0.59 cm to 0.53 cm (p = 0.002).
Greater improvement in supine-positioned patients; no significant changes were noted for prone-positioned patients.