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March 20, 2015CirculationOpen Access

Young women with ST-segment-elevation myocardial infarction are less likely to receive reperfusion therapy and more likely to have reperfusion delays than similarly aged men, with disparities more pronounced among those transferred to percutaneous coronary intervention institutions or receiving fibrinolytic therapy.

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Why the study?

Are young women with ST-segment-elevation myocardial infarction less likely to receive timely reperfusion therapy compared to similarly aged men?

Population

Young patients with ST-segment-elevation myocardial infarction

Comparison

Female sex vs Male sex (similarly aged)

Design

Cohort

Authors

GDGail D’OnofrioBSBasmah SafdarJLJudith H. Lichtman

Discussion

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Member takes

Overview

Observed reperfusion disparities for young women with STEMI support targeted quality initiatives; leaves open impact on outcomes.

Key Points

  • To assess the differences in reperfusion therapy rates and delays between young men and women with ST-elevation myocardial infarction.
  • Comparison of reperfusion therapy rates between young women and men with ST-segment-elevation myocardial infarction.
  • Analysis of delays in reperfusion therapy based on sex.
  • Examination of outcomes in patients transferred for percutaneous coronary intervention or receiving fibrinolytic therapy.
  • Young women receive reperfusion therapy less frequently than young men.
  • Reperfusion delays are more common in young women compared to their male counterparts.
  • Sex disparities are more significant in patients who are transferred for advanced treatments.

Structured PICO

Are young women with ST-segment-elevation myocardial infarction less likely to receive timely reperfusion therapy compared to similarly aged men?

P
Population
Young patients with ST-segment-elevation myocardial infarction
I
Intervention
Female sex
C
Comparator
Male sex (similarly aged)
O
Outcome
Receipt of reperfusion therapy and reperfusion delays

Highlights significant sex disparities in the timely administration of reperfusion therapy for young patients with STEMI, emphasizing the need for improved care pathways for women.

Cite This Study

D’Onofrio et al. (2015) studied this question.

synapsesocial.com/papers/69a0112486bd03045223446ahttps://doi.org/10.1161/circulationaha.114.012293
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