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March 25, 2026BJUI CompassOpen Access

Cytoreductive Radical Prostatectomy in Oligometastatic Prostate Cancer: Single‐Centre Experience

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Authors

KRKhawaja Abdul RoufALAkil LatiefSPSajad Ahmad Para

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Overview

Single-centre experience evaluates outcomes of cytoreductive surgery in oligometastatic prostate cancer, suggesting promising results.

Key Points

  • The aim is to assess outcomes, functional recovery, and satisfaction after cytoreductive radical prostatectomy in oligometastatic prostate cancer.
  • 12 patients with oligometastatic prostate cancer treated at a tertiary-care centre.
  • Underwent open retropubic cytoreductive radical prostatectomy after 6 months of neoadjuvant androgen deprivation therapy and targeted radiotherapy.
  • Adjuvant androgen deprivation therapy was provided for 2 years postoperatively.
  • Data on perioperative details, pathologies, and functional outcomes were recorded and analyzed.
  • Mean age of patients was 60 years with an operative time of 200 minutes and blood loss averaging 550 mL.
  • Final histopathology indicated organ-confined disease in all, with 16.7% showing positive surgical margins.
  • Continence was achieved in 83% at one year; potency was regained in all who had nerve-sparing surgery within 12 months.
  • No patients experienced biochemical recurrence over a mean follow-up of 25 months.
  • 83% reported complete satisfaction with the procedure.

Cite This Study

Rouf et al. (2026) studied this question.

synapsesocial.com/papers/69c37bd4b34aaaeb1a67e963https://doi.org/10.1002/bco2.70187
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Short-term clinical outcomes of cytoreductive radical prostatectomy combined with abiraterone-based androgen deprivation therapy in oligometastatic prostate cancer2026
  2. 2Cytoreductive radical prostatectomy in patients with high-volume metastatic prostate cancer achieving deep biochemical response to contemporary systemic therapy: a multicentre, prospective cohort study2026
  3. 3Role of Radical Prostatectomy in Oligo-Metastatic Hormone-Sensitive Prostate Cancer: A Systematic Review and Meta-Analysis2025 · 3 citations
  4. 4Results of a prospective, single-center phase-II study on modern androgen deprivation therapy followed by cytoreductive radical prostatectomy in men with de novo metastatic hormone-sensitive prostate cancer (mHSPC).2026
  5. 5Oncologic Outcomes of Cytoreductive Radical Prostatectomy in Patients With Synchronous Metastatic Castration‐Sensitive Prostate Cancer: A Retrospective Analysis2026