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April 5, 2026Cancer Research

Prognostic Significance of STING Expression in Resected Lung Adenocarcinoma

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Authors

JHJung-Jyh HungYKYing-Shiun Kao

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Overview

Demonstrates the relationship between STING expression and disease-free survival in lung adenocarcinoma, highlighting clinical significance.

Key Points

  • This research aims to evaluate the prognostic value of STING expression in patients with resected lung adenocarcinoma.
  • Included 68 patients with resected lung adenocarcinoma
  • STING expression was determined by immunohistochemistry
  • Examined relationship between STING expression and clinicopathological variables
  • Conducted Western blotting for STING, E-cadherin, and vimentin
  • High STING expression observed in 66.2% of lung tumor samples
  • High STING expression linked to improved disease-free survival (DFS) with HR 0.158
  • Multivariate analysis confirmed high STING expression as a significant prognostic factor (HR 0.073)

Cite This Study

Hung et al. (2026) studied this question.

synapsesocial.com/papers/69d1fcfda79560c99a0a2d13https://doi.org/10.1158/1538-7445.am2026-5379
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