Does drug-eluting stent placement in AMI patients result in delayed vessel healing and increased late stent thrombosis compared to DES placement in stable angina patients?
Underlying plaque morphology in AMI patients treated with DES leads to delayed arterial healing, which may increase the risk of late stent thrombosis compared to stable angina patients.
Vessel healing at the culprit site in AMI patients treated with DES is substantially delayed compared with the culprit site in patients receiving DES for stable angina, emphasizing the importance of underlying plaque morphology in the arterial response to DES. Our data suggest an increased risk of thrombotic complications in patients treated with DES for AMI.
Nakazawa et al. (2008) studied this question.