Local inflammation in epicardial adipose tissue is not reflected by systemic biomarkers or eliminated by current therapies in high-risk cardiac patients.
Epicardial adipose tissue is a source of several inflammatory mediators in high-risk cardiac patients. Plasma inflammatory biomarkers may not adequately reflect local tissue inflammation. Current therapies do not appear to eliminate local inflammatory signals in epicardial adipose tissue.
Mazurek et al. (2003) studied this question.