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April 19, 2018Thrombosis Journal124 citationsOpen Access

Association between plasminogen activator inhibitor-1 and cardiovascular events: a systematic review and meta-analysis

RJRichard G. JungPMPouya MotazedianFRF. Daniel Ramirez

Structured PICO

Are elevated plasma PAI-1 antigen levels associated with MACE?

I
Intervention
Elevated plasma PAI-1 antigen levels
O
Outcome
MACE (Major Adverse Cardiovascular Events)hard clinical

Elevated plasma PAI-1 antigen levels are associated with MACE, highlighting its potential as a risk marker or therapeutic target.

Abstract

Elevated plasma PAI-1 antigen levels are associated with MACE. Definitive studies are needed to ascertain if PAI-1 acts simply as a marker of risk or if it is indeed a bona fide therapeutic target.

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Cite This Study

Jung et al. (2018) studied this question.

synapsesocial.com/papers/69dd2cb8fb7610310c100f0ahttps://doi.org/10.1186/s12959-018-0166-4
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