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April 16, 2026Geriatrics and gerontology international/Geriatrics & gerontology international2 citations

Association of Mitochondrial DNA Levels in Peripheral Blood Leukocytes With Physical Performance in Older Adults

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HIHiroaki IkezakiRNRyoko NakashimaHNHideyuki Nomura

Key Points

  • The research aims to explore how mitochondrial DNA levels in blood cells correlate with physical performance in older adults.
  • Measured mitochondrial DNA copy number (mtDNA-CN) in peripheral blood leukocytes.
  • Evaluated physical performance through standardized tests for older adults.
  • A significant association was found between leukocyte mtDNA-CN levels and physical performance.
  • Higher mtDNA-CN levels were linked to better physical performance metrics.

Abstract

Leukocyte mtDNA-CN was associated with physical performance, suggesting its potential utility as a biomarker for frailty assessment in older adults.

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Cite This Study

Ikezaki et al. (2026) studied this question.

synapsesocial.com/papers/69e07cc02f7e8953b7cbde19https://doi.org/10.1111/ggi.70484
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