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April 16, 2026Alzheimer s & Dementia0 citationsOpen Access

The Canadian multi‐ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings

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TMTulip MarawiHRHarleen RaiRKRohina Kumar

Key Points

  • The study aims to investigate dementia risk and resilience factors among diverse ethnoracial groups in Canada.
  • Conducted a longitudinal observational study enrolling 300 adults aged 55-85.
  • Participants identified as South Asian, Chinese, or non-Hispanic White.
  • Included clinical assessments, MRI, and blood biomarker evaluations.
  • Implemented annual remote questionnaires for health and lifestyle tracking.
  • Vascular and metabolic profiles differed significantly across the participant groups.
  • South Asian and Chinese participants had greater cognitive concerns than non-Hispanic White participants.
  • Lower Montreal Cognitive Assessment scores were noted in South Asian and Chinese groups due to cultural item difficulties.
  • Eye-tracking measures showed no significant differences across the groups.

Abstract

Abstract INTRODUCTION South Asian and Chinese individuals are the largest and fastest‐growing ethnoracial groups in Canada, yet they remain underrepresented in dementia research. To address this gap, we established the CA nadian M ulti‐ E thnic R esearch on A ging (CAMERA) study. METHODS CAMERA is a longitudinal observational study conducted in Toronto, Canada, enrolling 300 adults aged 55‐85 who self‐identify as South Asian, Chinese, or non‐Hispanic White (NHW). Participants complete in‐person visits at baseline, Year 3, and Year 5, which include clinical and cognitive assessments, brain magnetic resonance imaging (MRI), and blood‐based biomarkers. Annual remote questionnaires track health and lifestyle factors. RESULTS Among the first 200 participants, vascular and metabolic profiles differed across groups. In addition, South Asian and Chinese participants reported greater cognitive concerns than NHW participants and had lower Montreal Cognitive Assessment (MoCA) scores. The latter was driven primarily by language‐heavy and culturally dependent items. Eye‐tracking measures did not differ across groups. DISCUSSION CAMERA provides a deep phenotyping framework to investigate dementia risk and resilience factors in Asian Canadians.

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Cite This Study

Marawi et al. (2026) studied this question.

synapsesocial.com/papers/69e07dad2f7e8953b7cbea45https://doi.org/10.1002/alz.71344
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