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April 17, 2026Annals of the American Thoracic Society1 citations

Biological Sex Differences in the US-CTEPH-R

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MCMeghan M. CirulisWAWilliam R AugerRBRaymond L. Benza

Key Points

  • The study aims to explore how biological sex influences CTEPH (Chronic Thromboembolic Pulmonary Hypertension) phenotypes and associated health outcomes.
  • Examined sex differences in CTEPH phenotypes
  • Analyzed health-related quality of life (HRQoL) assessments
  • Explored access to and feasibility of pulmonary thromboendarterectomy (PTE) interventions.
  • Identified distinct phenotypes associated with males and females
  • Found significant disparities in HRQoL based on sex
  • Highlighted the need for tailored interventions to improve outcomes.

Abstract

Males and females may have distinct CTEPH phenotypes which impact access to and feasibility of PTE. There are sex-associated disparities in the experience of CTEPH as a disease state, and differential impacts on HRQoL that warrant further investigation.

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Cite This Study

Cirulis et al. (2026) studied this question.

synapsesocial.com/papers/69e1cffa5cdc762e9d85902bhttps://doi.org/10.1093/annalsats/aaoag098
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