IMAT-HCC model: Liver Stiffness–Enhanced Integrated Risk Stratification for HCC Recurrence After Resection

This study demonstrates that integrating liver stiffness measurement with tumour-based criteria refines the identification of patients at high biological risk of recurrence after curative resection for hepatocellular carcinoma. By addressing the limitations of purely tumour-centric selection strategies (i.e IMbrave050 criteria), it highlights the prognostic relevance of the underlying liver disease in shaping post-resection outcomes. Incorporation of this approach into clinical research and trial design could improve risk stratification and patient selection for adjuvant therapies, while avoiding overgeneralisation given the retrospective, single-centre nature of the study.