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April 27, 2026Scientific ReportsOpen Access

Complete mitochondrial genome characterization and exploratory mitochondrial DNA modification signals in square-head catfish Chaca chaca

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Authors

PTPartha Sarathi TripathyLDLekiningroy DannSPSatya Narayan Parida

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Overview

Randomized trial characterizes mitochondrial genome and modification signals in Chaca chaca, suggesting insights for evolutionary study.

Key Points

  • To characterize the complete mitochondrial genome of Chaca chaca and explore mitochondrial DNA modification signals.
  • Sequenced high-molecular-weight DNA using Oxford Nanopore adaptive sampling.
  • Performed de novo assembly and annotation of the mitogenome.
  • Conducted comparative analyses and methylation profiling of mtDNA.
  • The complete mitogenome is 16,591 bp long with standard elements including 13 protein-coding genes.
  • Phylogenetic analysis placed C. chaca within Chacidae, adjacent to Pimelodidae and Pseudopimelodidae.
  • Identified 5-methylcytosine and N6-methyladenine signals, with significant differences in modification frequency observed.

Cite This Study

Tripathy et al. (2026) studied this question.

synapsesocial.com/papers/69eefcaefede9185760d3985https://doi.org/10.1038/s41598-026-50124-x
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