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April 29, 2026European Heart Journal

The carotid intima-media thickness as a marker of the presence of severe symptomatic coronary artery disease

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Why the study?

Does carotid intima-media thickness correlate with the presence and severity of coronary artery disease in male patients assessed for chest pain?

Population

75 consecutive male patients undergoing coronary angiography for chest pain and 40 matched normal controls

Comparison

Patients undergoing coronary angiography vs age- and sex-matched normal controls

Authors

GGGeorge GeroulakosDOD. J. O'GormanEKEvi Kalodiki

Discussion

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Member takes

Overview

May aid noninvasive CAD assessment in high-risk men; leaves open routine adoption pending prospective validation in broader populations.**[[1]](https://pubmed.ncbi.nlm.nih.gov/8088266/)[[2]](https://academic.oup.

Structured PICO

Does carotid intima-media thickness correlate with the presence and severity of coronary artery disease in male patients assessed for chest pain?

P
Population
75 consecutive male patients undergoing coronary angiography for assessment of chest pain and 40 age- and sex-matched normal controls (total n=115).
I
Intervention
Measurement of carotid intima-media thickness (IMT) using high-resolution B-mode ultrasound
C
Comparator
Normal controls and patients with normal coronary angiograms
O
Outcome
Carotid intima-media thickness (IMT)surrogate

Carotid intima-media thickness measured by ultrasound is significantly increased in patients with coronary artery disease and correlates with the number of involved vessels, suggesting its utility as a non-invasive marker for CAD.

Cite This Study

Geroulakos et al. (1994) studied this question.

synapsesocial.com/papers/69f1cd07a53d347ef6df0882https://doi.org/10.1093/oxfordjournals.eurheartj.a060585
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