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May 6, 2026PAIN Reports0 citationsOpen Access

Sleep Heart Rate Predicts Pain Medications in Veterans with PTSD

Sleep heart rate predicts next-day pain medication use in posttraumatic stress disorder inpatients

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Authors

GTGisselle TamayoNANed J. ArsenaultAJAndrea L. Jamison

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Overview

Randomized trial explores how sleep heart rate affects pain medication use in Veterans, indicating potential for targeted intervention.

Key Points

  • This study aims to investigate how sleep heart rate and respiratory sinus arrhythmia influence next-day pain medication use among Veterans with PTSD.
  • Seventy-eight male US military Veterans were observed over an average of 78 nights in an inpatient treatment program.
  • Sleep heart rate and respiratory sinus arrhythmia were recorded using mattress actigraphy, and pain medication prescriptions were obtained from health records.
  • Binary logistic mixed-effects regression models analyzed the impact of sleep heart rate and RSA on next-day pain medication use.
  • Higher sleep heart rate predicted increased rates of next-day pain medication prescriptions.
  • No significant effect of sleep respiratory sinus arrhythmia on pain medication use was found.
  • Between-person effects were significant, while within-person effects were not.

Cite This Study

Tamayo et al. (2026) studied this question.

synapsesocial.com/papers/69fada7f03f892aec9b1e429https://doi.org/10.1097/pr9.0000000000001444
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Circadian Contrasts in Heart Rate Variability Associated With Posttraumatic Stress Disorder Symptoms in a Young Adult Cohort2016 · 27 citations
  2. 2Posttraumatic stress disorder diagnosis is associated with reduced parasympathetic activity during sleep in US veterans and military service members of the Iraq and Afghanistan wars2018 · 55 citations
  3. 3Stress-induced increase in heart-rate during sleep as an indicator of PTSD risk among combat soldiers2024 · 16 citations
  4. 4Sleep efficiency is negatively associated with resting daytime heart rate in trauma‐exposed premenopausal women2025 · 1 citations
  5. 5Objective Sleep Effciency Is Negatively Associated with Resting Heart Rate in Young Trauma-Exposed Women with Poor Sleep2024