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May 6, 2026Journal of Surgical Case ReportsOpen Access

Rare metachronous isolated splenic metastasis of sigmoid carcinoma: a case report and literature review

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Authors

YYYichao YanXWXinchun WuJZJunxi Zhu

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Overview

Case report highlights effective comprehensive treatment for isolated splenic metastasis in a male patient, suggesting improved outcomes.

Key Points

  • To present a rare case of isolated splenic metastasis from sigmoid carcinoma and review related literature.
  • Reported a case of a 58-year-old male with metachronous isolated splenic metastasis
  • Implemented splenectomy, chemotherapy, targeted therapy, and anti-PD-1 antibody
  • Reviewed literature on isolated splenic metastasis from colorectal cancer.
  • Patient achieved tumor-bearing survival for 32 months after combined therapy
  • Emphasized the need for comprehensive treatment to mitigate new metastasis risks
  • Highlighted the rarity of isolated splenic metastases in solid malignancies.

Cite This Study

Yan et al. (2026) studied this question.

synapsesocial.com/papers/69fada7f03f892aec9b1e475https://doi.org/10.1093/jscr/rjaf1098
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