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May 7, 20260 citations

The Leiden Stroop-like Stress Task: A Tool to Reveal Physiological Dynamics Using Graded Stress Induction.

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JYJin YanFBFrenn BultinckLMLiwen Meng

Key Result

The Leiden Stroop-like Stress Task effectively elicited gradual increases in self-reported stress, heart rate, and vascular resistance across four 10-minute blocks in 54 healthy adults.

Key Points

  • This research aims to evaluate the effectiveness of the Leiden Stroop-like Stress Task in inducing graded stress and capturing physiological responses.
  • Participants included 54 healthy adults (mean age 21 ± 3 years).
  • The LSST involved four 10-minute blocks with varying task difficulty and social-evaluative threat.
  • Physiological measures included heart rate, blood pressure, and continuous cardiovascular recordings.
  • Self-reported stress and negative affect increased significantly with progressively higher stress levels.
  • Heart rate and vascular resistance exhibited a continuous increase over the stress induction period.
  • Challenge-threat appraisals shifted towards threat, yet remained predominantly on the challenge side of the continuum.

Study Design

Type

Observational (n=54)

Structured PICO

Does the Leiden Stroop-like Stress Task effectively induce graded physiological and psychological stress responses in healthy adults?

P
Population
54 healthy adults (35 females; mean age = 21 ± 3 years)
I
Intervention
Leiden Stroop-like Stress Task (LSST) involving progressively increasing levels of task difficulty and social-evaluative threat across four 10-minute blocks
O
Outcome
Self-reported stress, challenge-threat appraisal, and continuous cardiovascular recordings (heart rate, blood pressure, pre-ejection period, vascular resistance, cardiac output)surrogate

The Leiden Stroop-like Stress Task is an effective paradigm for inducing graded mild to moderate stress and capturing its psychological and cardiovascular hemodynamic dynamics.

Abstract

Stress evokes a complex repertoire of psychological and physiological responses. This paper introduces the Leiden Stroop-like Stress Task (LSST), a paradigm designed to induce progressively increasing levels of stress by manipulating task difficulty and social-evaluative threat across four 10-minute blocks. Fifty-four healthy adults (35 females; mean age = 21 ± 3 years) completed the LSST, with repeated assessments of self-reported stress and challenge-threat appraisal, as well as continuous cardiovascular recordings. Results confirmed the LSST's effectiveness in eliciting gradual increases in self-reported stress, negative affect, and heart rate, along with gradual decreases in positive affect. Changes in blood pressure and pre-ejection period also increased moderately but showed a more discrete change over time. Challenge-threat appraisals gradually shifted from challenge to threat but, on average, remained on the challenge side of the bipolar continuum. Vascular resistance, as measured by total peripheral resistance, exhibited a continuous increase. This vascular effect accompanied (slightly) increased ventricular contractility and heart rate as well as stable cardiac output, thus reflecting a classic physiological threat pattern. Exploratory within-subject correlations revealed consistent alignment between self-reported stress and physiological measures. Our findings demonstrate that the LSST enables the graded induction of mild to moderate stress and effectively captures stress dynamics across psychological and physiological levels. We discuss the potential of this paradigm to provide insights into stress dynamics and its vascular hemodynamic profile, as well as interventions aimed at increasing stress resilience.

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Cite This Study

Yan et al. (2026) conducted an observational in Healthy adults (n=54). Leiden Stroop-like Stress Task (LSST) was evaluated on Self-reported stress, challenge-threat appraisal, and continuous cardiovascular recordings. The Leiden Stroop-like Stress Task effectively elicited gradual increases in self-reported stress, heart rate, and vascular resistance across four 10-minute blocks in 54 healthy adults.

synapsesocial.com/papers/69fc2c1f8b49bacb8b347bb8https://doi.org/10.1016/j.biopsycho.2026.109279
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