In today's society, with changes in diet structure and living habits, drug abuse, and psychosomatic diseases, the prevalence of constipation is increasing. Currently, there is a lack of unified diagnostic criteria for constipation, and therapeutic approaches lack standardization. This often leads to an inability to select appropriate treatment methods based on the patient's specific condition. Consequently, a significant proportion of constipation patients do not achieve satisfactory therapeutic outcomes. This is particularly true for slow-transit constipation (STC), which is characterized by a protracted course of the disease and significant diagnostic challenges. Therefore, this review aims to delineate the mechanisms, diagnosis, and therapeutic advances in STC, in order to offer insights for clinical diagnosis and treatment.
Yang et al. (2026) studied this question.