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May 20, 2026American Journal of Respiratory and Critical Care Medicine0 citations

B51-26 Resection and Reconstruction of Intraseptal Aortic Root Mycotic Pseudoaneurysm in a Patient With Suspected Prosthetic Valve Endocarditis and Complete Heart Block

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GNG Gautier NievesNEN EnofeJOJ Obeid

Key Result

Surgical resection and patch reconstruction of an intraseptal aortic root mycotic pseudoaneurysm resulted in uncomplicated recovery and no recurrence at 2-month follow-up.

Key Points

  • This case aims to highlight the rare complication of intraseptal extension of aortic root mycotic pseudoaneurysm due to infective endocarditis.
  • Conducted detailed echocardiography and computed tomography for diagnosis.
  • Performed re-do sternotomy for resection of the thrombosed pseudoaneurysm.
  • Utilized pericardial and Hemashield patches for reconstruction.
  • Surgery successfully removed the pseudoaneurysm, confirming thrombosis via pathology.
  • Patient recovered without complications post-operation and completed a six-week antibiotic course.
  • Follow-up echocardiography showed no recurrent aneurysm at two months.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
1 80-year-old female with a remote history of mechanical aortic valve replacement, presenting with recurrent falls, night sweats, complete heart block, Staphylococcus epidermidis bacteremia, and a 4 cm aortic root pseudoaneurysm.
I
Intervention
Re-do sternotomy with resection of thrombosed pseudoaneurysm, pericardial patch repair of residual atrial septal defect, Hemashield patch reconstruction for aortic root, epicardial pacemaker implantation, and a six-week course of antibiotics.
O
Outcome
Postoperative recovery and recurrence of aneurysm at 2 months

This case demonstrates the successful surgical management of a rare and severe intraseptal extension of an aortic root mycotic pseudoaneurysm complicating prosthetic valve endocarditis.

Abstract

Abstract Introduction Intraseptal abscesses and destructive aortic lesions are rare complications of infective endocarditis, associated with increased morbidity and mortality. Case Description We present the case of an 80-year-old female with a remote history of mechanical aortic valve replacement who presented with recurrent falls and night sweats. On further evaluation, she was found to have complete heart block and Staphylococcus epidermidis bacteremia. Transthoracic echocardiography and computed tomography with angiography (CTA) of chest identified a 4 cm aortic root pseudoaneurysm versus abscess (Figure 1b). The patient underwent a re-do sternotomy, which revealed a large 6 x 6 cm thrombosed aortic root pseudoaneurysm with a 1 cm neck at the aortic root. The pseudoaneurysm extended into the interatrial septum and protruded into the right atrium with significant obliteration of the right atrial cavity. The thrombosed pseudoaneurysm was resected, and repair was performed using a pericardial patch repair of the residual atrial septal defect and a Hemashield patch reconstruction for the aortic root pseudoaneurysm excision site reconstruction (Figure 1a). An epicardial pacemaker was also implanted. Pathology confirmed thrombosed pseudoaneurysm. Postoperatively, the patient recovered without complication. She completed a six-week course of antibiotics with negative blood cultures. At two-month follow-up, transthoracic echocardiography showed no evidence of recurrent aneurysm. Discussion Infective endocarditis carries a moderate risk of progression to myocardial abscess formation. The proximity of the intraventricular and interatrial septa to the cardiac valves renders them particularly vulnerable to the spread of infection. Such cases usually require prolonged ventilation and increased intensive care unit length of stay. This case highlights the presentation and management of a rare yet severe complication-intraseptal extension of aortic root mycotic pseudoaneurysm-in the setting of prosthetic valve. It calls attention to the importance of maintaining a high index of suspicion and prompt management in patients presenting with non-specific symptoms suggestive of infective endocarditis. This abstract is funded by: No Funding

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Cite This Study

Nieves et al. (2026) conducted a case report in Intraseptal aortic root mycotic pseudoaneurysm and suspected prosthetic valve endocarditis (n=1). Surgical resection and patch reconstruction with epicardial pacemaker implantation was evaluated on Postoperative recovery and recurrence of aneurysm. Surgical resection and patch reconstruction of an intraseptal aortic root mycotic pseudoaneurysm resulted in uncomplicated recovery and no recurrence at 2-month follow-up.

synapsesocial.com/papers/6a0d4fbff03e14405aa9b288https://doi.org/10.1093/ajrccm/aamag162.1446
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