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October 17, 2025Cost Effectiveness and Resource AllocationOpen Access

Cost-effectiveness analysis of an implantable cardiac defibrillator compared with pharmaceutical therapy in patients hospitalized with arrhythmia in Iran

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Authors

TNTayyebeh NowruziRGReza GoudarziMAMaryam Aliramezany

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Overview

Economic evaluation compares implantable cardiac defibrillator cost-effectiveness with pharmaceutical therapy in arrhythmia patients in Iran.

Key Points

  • The ICD strategy costs $41,135 with 12.63 QALYs, while pharmaceutical therapy costs $8,592 yielding 11.29 QALYs.
  • The incremental cost-effectiveness ratio for ICD compared to pharmaceutical therapy is $24,286 per QALY, indicating it is not cost-effective.
  • Probabilistic sensitivity analysis shows a 40% chance of cost-effectiveness for ICD at a willingness-to-pay threshold of three times GDP per capita in Iran.
  • Resource allocation and cost-cutting measures may be necessary as the ICD approach is not economical for treating arrhythmia patients.

Cite This Study

Nowruzi et al. (2025) studied this question.

synapsesocial.com/papers/68f25c913dc7eb0776cbc0f6https://doi.org/10.1186/s12962-025-00661-5
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