Effect of edaravone dexborneol on clinical outcomes in patients with acute posterior circulation ischemic stroke undergoing endovascular therapy: A retrospective single-center study
Retrospective study investigates edaravone dexborneol's effects on functional recovery in acute posterior circulation ischemic stroke patients undergoing EVT, indicating positive outcomes.
Key Points
This study aims to evaluate the clinical efficacy and safety of edaravone dexborneol in patients with posterior circulation acute ischemic stroke undergoing endovascular therapy.
Single-center, retrospective, case-control design
Involved 101 patients with posterior circulation AIS who underwent EVT
Patients divided into EdaBorneol group (n=53) and control group (n=48)
Logistic regression analyses assessing the impact on hemorrhagic transformation and functional outcomes
Subgroup analyses for patients receiving bridging therapy and achieving successful recanalization.
EdaBorneol group had significantly lower hemorrhagic transformation rate (odds ratio 0.12, P=0.003)
Higher proportion of patients in the EdaBorneol group achieved good functional recovery (modified Rankin Scale ≤ 3; P=0.001)
Enhanced efficacy observed in patients who were reperfused (odds ratio 0.03, P=0.002).