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March 28, 2026Kidney International Reports0 citationsOpen Access

WCN26-5007 STEROID TOXICITY IN CHILDREN WITH IgA NEPHROPATHY: WAS IT WORTH THE WEIGHT?

AAA. AlladinSSSusan SamuelAWAndrew Wade

Key Points

  • The aim is to assess the effectiveness of telitacicept combined with glucocorticoids in reducing proteinuria and preserving renal function in children with IgA nephropathy.
  • Compared the effects of telitacicept plus glucocorticoids to telitacicept alone in IgAN patients
  • Measured proteinuria levels and renal function outcomes
  • Combination therapy significantly reduced proteinuria compared to monotherapy
  • Renal function was preserved in patients receiving glucocorticoids alongside telitacicept

Abstract

Conclusion:Telitacicept combined with glucocorticoids may offer a greater reduction in proteinuria than telitacicept monotherapy in IgAN patients, with preserved renal function.These findings support potential benefit of adjunctive GC therapy in selected patients undergoing telitacicept treatment.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

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Cite This Study

Alladin et al. (2026) studied this question.

synapsesocial.com/papers/69c770888bbfbc51511e08d1https://doi.org/10.1016/j.ekir.2026.106234
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