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May 28, 2021Nature Reviews Cardiology1,537 citationsOpen Access

Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension

BZBin ZhouPPPablo PerelGMGeorge A. Mensah

Structured PICO

P
Population
Global population, specifically comparing high-income regions to low-income and middle-income countries.
I
Intervention
Population-level interventions (increasing availability of fresh fruits/vegetables, lowering sodium content, dietary salt substitutes) and scaling up hypertension treatment coverage.

The global burden of hypertension has shifted to low- and middle-income countries, highlighting the need for population-level dietary interventions and improved treatment coverage.

Abstract

High blood pressure is one of the most important risk factors for ischaemic heart disease, stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood pressure and the prevalence of raised blood pressure have declined substantially in high-income regions since at least the 1970s. By contrast, blood pressure has risen in East, South and Southeast Asia, Oceania and sub-Saharan Africa. Given these trends, the prevalence of hypertension is now higher in low-income and middle-income countries than in high-income countries. In 2015, an estimated 8.5 million deaths were attributable to systolic blood pressure >115 mmHg, 88% of which were in low-income and middle-income countries. Measures such as increasing the availability and affordability of fresh fruits and vegetables, lowering the sodium content of packaged and prepared food and staples such as bread, and improving the availability of dietary salt substitutes can help lower blood pressure in the entire population. The use and effectiveness of hypertension treatment vary substantially across countries. Factors influencing this variation include a country's financial resources, the extent of health insurance and health facilities, how frequently people interact with physicians and non-physician health personnel, whether a clear and widely adopted clinical guideline exists and the availability of medicines. Scaling up treatment coverage and improving its community effectiveness can substantially reduce the health burden of hypertension.

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Cite This Study

Zhou et al. (2021) studied this question.

synapsesocial.com/papers/69c9e634d42de1a0cf2edb2ahttps://doi.org/10.1038/s41569-021-00559-8
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