Does cryoballoon ablation provide noninferior efficacy compared to radiofrequency ablation in patients with drug-refractory paroxysmal atrial fibrillation?
Cryoballoon ablation is a safe and effective alternative to radiofrequency ablation, demonstrating noninferiority for the treatment of drug-refractory paroxysmal atrial fibrillation.
In this randomized trial, cryoballoon ablation was noninferior to radiofrequency ablation with respect to efficacy for the treatment of patients with drug-refractory paroxysmal atrial fibrillation, and there was no significant difference between the two methods with regard to overall safety. (Funded by Medtronic; FIRE AND ICE ClinicalTrials.gov number, NCT01490814.).
Kuck et al. (2016) studied this question.
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