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August 1, 2019ACS Nano

Versatile Polydopamine Platforms: Synthesis and Promising Applications for Surface Modification and Advanced Nanomedicine

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Authors

WCWei ChengXZXiaowei ZengHCHongzhong Chen

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Overview

Review reveals multifunctional capabilities of polydopamine platforms in biomedical materials, highlighting their value for targeted therapies and surface modification.

Key Points

  • To summarize recent developments in the synthesis, polymerization mechanisms, physicochemical properties, and biomedical applications of mussel-inspired polydopamine platforms.
  • Reviewed literature spanning 2016 to 2019 covering polydopamine preparation, polymerization chemistry, and nano/microstructure fabrication.
  • Assessed surface modification protocols and emerging functional implementations in nanomedicine and drug delivery.
  • Polydopamine exhibits robust surface adhesion, high biocompatibility, facile functionalization, excellent photothermal conversion efficiency, and strong fluorescence quenching.
  • Advanced polydopamine platforms effectively coat diverse material substrates to provide multifunctional capabilities for theranostics and targeted biomedical interventions.

Cite This Study

Cheng et al. (2019) studied this question.

synapsesocial.com/papers/69d8a0e75c3030ff03d1a350https://doi.org/10.1021/acsnano.9b04436
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