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July 6, 2021Journal of Clinical Oncology78 citations

Efficacy and Toxicity of Pegaspargase and Calaspargase Pegol in Childhood Acute Lymphoblastic Leukemia: Results of DFCI 11-001

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LVLynda M. VroomanTBTraci M. BlonquistKSKristen E. Stevenson

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Abstract

Every 3-week calaspargase had similar nadir SAA, toxicity, and survival outcomes compared with every 2-week pegaspargase. The high nadir SAA observed for both preparations suggest dosing strategies can be further optimized.

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Vrooman et al. (2021) studied this question.

synapsesocial.com/papers/69d8e82833ca018b39ae44ebhttps://doi.org/10.1200/jco.20.03692
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