PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 17, 2026Neurosurgery Open0 citationsOpen Access

Particle Embolization of the Middle Meningeal Artery for Subdural Hematoma: Efficacy and Cost Considerations

View Full Paper
VSVarun ShahJSJerry ShepherdQNQuang Nguyen

Key Points

  • The study aims to evaluate the efficacy and cost-effectiveness of using PVA particles for MMAE in chronic subdural hematoma treatment.
  • Retrospective review of patients undergoing MMAE between 2020-2022
  • Collection of demographics, medical history, symptoms, procedural details, and radiographic data
  • Assessment of rescue surgical intervention and SDH thickness reduction as primary endpoints
  • Fifty-nine patients evaluated, with 91.5% showing at least a 50% reduction in SDH size
  • Only 6.8% required rescue surgical intervention post-procedure
  • PVA particles demonstrated significant cost savings compared to Onyx

Abstract

BACKGROUND AND OBJECTIVES: Subdural hematoma (SDH) is an increasingly common pathology. Middle meningeal artery embolization (MMAE) is an endovascular procedure shown to be efficacious in treating chronic subdural hematoma. This study aims to explore the efficacy of MMAE using polyethylene vinyl (PVA) particle and highlight cost effectiveness. METHODS: A single-center retrospective review was conducted. Patients who underwent MMAE from 2020 to 2022 were included. Demographics, medical history, symptoms on presentation, procedural details, and radiographic variables were collected. Rescue surgical evacuation and decreased SDH thickness by 50% were the primary end points. RESULTS: Fifty-nine patients were included, with 43 male and 16 female patients, with an average age of 72. 9 ± 9. 6 years. Preprocedure SDH thickness was 14. 7 ± 6. 2 mm and midline shift was 6. 2 ± 4. 5 mm. Thirty-one patients (52. 5%) were on home antiplatelet medications; 19 patients (32. 3%) were on anticoagulants. PVA particles were the only embolisate used. Three patients underwent general anesthesia, and monitored anesthesia care was utilized for the rest. Postprocedurally, 4 patients required rescue surgical intervention (6. 8%). Fifty-four (91. 5%) patients had a decrease in SDH size by at least 50% at the last follow up visit. No patients had neurological deterioration postprocedurally. CONCLUSION: This study suggests PVA for primary treatment of chronic subdural hematoma is safe and effective. The cost of 45–150 micron PVA particles is 153, compared with a vial of Onyx, which is 3334. Large-scale trials comparing embolic agents are necessary to assess for efficacy and safety in the setting of cost differences.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Shah et al. (2026) studied this question.

synapsesocial.com/papers/69e1cf7b5cdc762e9d85871chttps://doi.org/10.1227/neuprac.0000000000000226
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Middle Meningeal Artery Embolization for Chronic Subdural Hematoma2017 · 435 citations
  2. 2Perioperative prophylactic middle meningeal artery embolization for chronic subdural hematoma: a series of 44 cases2021 · 57 citations
  3. 3The surgical management of chronic subdural hematoma2011 · 534 citations
  4. 4Middle meningeal artery embolization for chronic subdural hematoma: an effective treatment with a bright future2024 · 61 citations
  5. 5Total 1-year hospital cost of middle meningeal artery embolization compared to surgery for chronic subdural hematomas: a propensity-adjusted analysis2021 · 61 citations