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April 17, 2026ACS Nanoscience Au0 citationsOpen Access

High-Throughput Detection of Schistosomiasis Biomarkers Using Nanoscale Metallization

Multiplexed High-Throughput Detection of Schistosomiasis Biomarkers Using Enhanced Nanoscale Enzymatic Metallization

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Authors

MSMallika SenthilHZHanhao ZhangIBIrene Carriazo Badillo

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Overview

Multiplexed platforms detect schistosomiasis biomarkers, indicating improved differentiation of infection status.

Key Points

  • The aim is to develop an inexpensive method to accurately detect schistosomiasis infection status.
  • Utilized two multiplexed high-throughput platforms for detection.
  • Developed an optical detection platform using cellphone images.
  • Created an electrical detection platform using gold nanoparticles.
  • Compared the effectiveness of both detection methods.
  • Optimized multiplexed readouts to measure antibody subclasses against schistosome antigens.
  • The optical platform performed better at differentiating infection statuses among three patient groups.
  • A multiplexed readout version successfully differentiated infection status based on antibody levels.

Cite This Study

Senthil et al. (2026) studied this question.

synapsesocial.com/papers/69e1cfb15cdc762e9d858ac5https://doi.org/10.1021/acsnanoscienceau.6c00013
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