Does reversible ischemia induced during DSE increase IL-6 and TF plasma levels in patients with coronary artery disease?
Myocardial ischemia induced by stress testing increases inflammatory and prothrombotic biomarkers (IL-6 and TF), which correlate with the severity of left ventricular dysfunction.
Reversible ischemia induced during DSE increases IL-6 and TF plasma levels. IL-6 is related to the extent of left ventricular dysfunction at peak stress and to persistent LV dysfunction during recovery.
Ikonomidis et al. (2005) studied this question.