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April 15, 2026IJC Heart & VasculatureOpen Access

Fast-heart-rate-dependent-PVC was the most common PVC profile in MVP patients, whereas slow-heart-rate-dependent-PVC was rare.

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Why the study?

How does heart rate affect the frequency of premature ventricular complexes in patients with mitral valve prolapse?

Population

Patients with MVP

Authors

CBCecilie BuggeCFChristian K FiveTATariq Ahmed

Discussion

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Overview

May indicate catecholamine-sensitive PVC triggers in MVP; leaves open prospective validation for arrhythmia risk.

Structured PICO

How does heart rate affect the frequency of premature ventricular complexes in patients with mitral valve prolapse?

P
Population
Patients with mitral valve prolapse (MVP)
O
Outcome
Premature ventricular complex (PVC) profile in relation to heart ratesurrogate

In patients with mitral valve prolapse, premature ventricular complexes are predominantly fast-heart-rate-dependent, suggesting a catecholamine-sensitive trigger mechanism for ventricular arrhythmias.

Cite This Study

Bugge et al. (2026) studied this question.

synapsesocial.com/papers/69eff939bce9831ba4f735e8https://doi.org/10.1016/j.ijcha.2026.101925
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