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August 4, 2021Journal of the American Chemical Society104 citations

Identifying G-Quadruplex-DNA-Disrupting Small Molecules

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JMJérémie MitteauxPLPauline LejaultFWFilip Wojciechowski

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Abstract

. This unique, multipronged approach leads to the characterization of a phenylpyrrolocytosine (PhpC)-based G-clamp analog as a prototype of G4-disrupting small molecule whose properties are validated through many different and complementary in vitro evaluations.

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Cite This Study

Mitteaux et al. (2021) studied this question.

synapsesocial.com/papers/6a0358c1200d7a04bd7562abhttps://doi.org/10.1021/jacs.1c04426
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