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August 1, 2025Journal of Neurochemistry

The Role of Extracellular Vesicles in Brain‐Peripheral Communication Following Ischemic Stroke: Implications for Neural Repair and Regeneration

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Authors

VRVictória Linden de RezendeKMKhiany MathiasMCMaiara de Aguiar da Costa

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Overview

Narrative review highlights extracellular vesicles' role in neuroinflammation and tissue repair after ischemic stroke, suggesting therapeutic potential.

Key Points

  • Extracellular vesicles play a key role in communication between the brain and peripheral organs after ischemic stroke.
  • These vesicles can transport bioactive molecules across the blood-brain barrier, influencing neuroinflammation.
  • Peripheral extracellular vesicles derived from various tissues can significantly impact brain recovery processes.
  • There is a need for standardized protocols and further research to advance the clinical application of extracellular vesicles.

Cite This Study

Rezende et al. (2025) studied this question.

synapsesocial.com/papers/689a0c6be6551bb0af8cfc5ahttps://doi.org/10.1111/jnc.70155
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