Idiopathic lower extremity ulcers are a common yet challenging clinical condition that generally requires multidisciplinary treatment. In this case report, we present the case of a 77-year-old male patient with idiopathic lower limb ulcers of undetermined cause. The patient also had a notable medical comorbidity of essential hypertension and a past surgical history of nephrectomy for renal carcinoma, yet no past medical history of proven venous disease. Despite extensive diagnostic investigation, utilizing both vascular evaluation and wound swab cultures, the precise etiology of his ulcerations could not be determined. Due to the chronicity and nonhealing nature of the wounds, the ulcers were managed with a combination of the standard treatment modalities commonly used for venous stasis ulcers. The patient was managed with a trial of compression therapy, ulcer debridement, and high-tech dressing, after which he had remarkable improvement. This case illustrates the potential benefit of establishing a standardized treatment modality for lower extremity venous ulcers with an undetermined etiology.
Rashid et al. (2025) studied this question.