This study aims to evaluate the efficacy and feasibility of hysteroscopic Mirena suture fixation as a therapeutic approach for adenomyosis. A retrospective analysis was conducted on the clinical data of 42 patients diagnosed with adenomyosis at the People's Hospital of Rizhao. Comparisons were drawn between two groups: the conventional LNG-IUS placement group (n=21) and the hysteroscopic LNG-IUS suture fixation group (n=21). Key parameters, including dysmenorrhea, menstrual blood volume, uterine volume, and adverse effects, were assessed both prior to and following treatment. Both groups exhibited marked improvements in dysmenorrhea relief, reduction in menstrual blood volume, and decreased uterine volume at 3 and 6 months post-treatment (P0.05). Notably, the hysteroscopic LNG-IUS suture fixation group had markedly lower rates of Mirena displacement and expulsion (P<0.05). Hysteroscopic LNG-IUS suture fixation was found to markedly alleviate dysmenorrhea and reduce menstrual blood volume, while also lowering the risk of Mirena displacement and expulsion. This technique enhances the overall therapeutic efficacy of LNG-IUS for treating adenomyosis, offering key benefits of safety, effectiveness, and minimal invasiveness, thus supporting its clinical application.
Wang et al. (2025) studied this question.