October 17, 2025Open Access

Supplementary Figure 8 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

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Genomic alterations detected in tumor tissue and plasma DNA help evaluate treatment responses.
Patients treated with binimetinib show distinct response patterns based on NRAS mutation status.
The presence of mutations is depicted using triangles for clarity in genomic assessment.
This analysis highlights the importance of multi-sample genotyping in precision medicine.

Resumen

Supplementary Figure 8. Genomic alterations detected in patients treated in subprotocol Z1A enrolling patients with NRAS mutations who received treatment with binimetinib. Patients are stratified according to the best overall response. Triangles are used to depict the presence of mutation in tissue (lower triangle) and/or plasma (upper triangle).

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Gouda et al. (Wed,) studied this question.

www.synapsesocial.com/papers/68f199bfde32064e504dcc78 — DOI: https://doi.org/10.1158/1078-0432.30363462

Authors

Mohamed A. Gouda

Filip Janků

Ying Yuan

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Supplementary Figure 8 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Actions

References and Citations

Citation Network

Connected Papers

Discussion