| 1 | In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia New England Journal of Medicine · Vafai S et al. | May 25 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 2 | Stem-Cell–Derived Biologic Ventricular Assist Tissue in Heart Failure New England Journal of Medicine · Zimmermann W et al. | May 27 | | Yes (NEJM) | — | — | — | — |
| 3 | Are Changes in Cardiovascular Disease Risk Factors in Midlife Women Due to Chronological Aging or to the Menopausal Transition? Journal of the American College of Cardiology · Matthews K et al. | Dec 1 | — | Yes (JACC) | 40 | — | — | — |
| 4 | Secondary Prevention after Ischemic Stroke New England Journal of Medicine | May 27 | | Yes (NEJM) | — | — | — | — |
| 5 | Left Ventricular Unloading in High-Risk Percutaneous Coronary Intervention New England Journal of Medicine · Perera D et al. | Mar 29 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 6 | Role of Physical Activity in Obesity Treatment and Cardiometabolic Health: A Scientific Statement From the American Heart Association Circulation · Swift D et al. | Jun 1 | | Yes (Circulation) | — | — | — | — |
| 7 | Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation New England Journal of Medicine · Doshi S et al. | Mar 28 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 8 | Kidney and Survival Benefits of Semaglutide in Diabetes With Chronic Kidney Disease Journal of the American College of Cardiology · Tuttle K et al. | Jun 1 | | Yes (ACC Journal Scan) | — | — | — | — |
| 9 | Lipoprotein(a) and residual cardiovascular risks in Japanese patients with coronary artery disease who achieve guideline-recommended low-density lipoprotein cholesterol goals European Heart Journal · Kataoka Y et al. | May 19 | | Yes (European Heart Journal) | — | — | — | — |
| 10 | Lifestyle-Induced Visceral Fat Loss as a Key Target for Durable Cardiometabolic Health: MRI-Assessed 5- and 10-Year Follow-Up After 2 Clinical Trials Circulation · Klein H et al. | Jun 2 | | Yes (Circulation) | — | — | — | — |
| 11 | Dysregulated T Cell–Mediated Immunity Underlies Progression of Arrhythmogenic Right Ventricular Cardiomyopathy Circulation · Protonotarios A et al. | Jun 1 | | Yes (Circulation) | — | — | — | — |
| 12 | Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease Journal of the American College of Cardiology · Gümüşer E et al. | May 1 | | Yes (JACC) | — | — | — | — |
| 13 | Lipoprotein(a) Levels, Risk of Cardiovascular Events and Benefit of Evolocumab: Findings From the VESALIUS-CV Trial Circulation · Monguillon V et al. | May 25 | | Yes (Circulation) | — | — | — | — |
| 14 | Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T) Journal of the American College of Cardiology · Alvi R et al. | Dec 1 | | Yes (JACC) | — | — | — | — |
| 15 | Sirolimus-Coated Balloon Angioplasty for Infrainguinal Artery Disease New England Journal of Medicine · Barco S et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 16 | Effect of APOC3 Inhibition with Olezarsen on Coronary Atherosclerosis: Essence–TIMI 73b Imaging Study Circulation · Marston N et al. | Mar 30 | — | Yes (Circulation) | — | Yes (TWiC) | — | — |
| 17 | Discontinuation of Beta-Blocker Therapy after Myocardial Infarction New England Journal of Medicine · Choi K et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 18 | Mavacamten in Adolescents with Obstructive Hypertrophic Cardiomyopathy New England Journal of Medicine · Rossano J et al. | Mar 29 | | Yes (NEJM) | — | — | — | — |
| 19 | Initial Surgical Versus Conservative Strategies in Patients With Asymptomatic Severe Aortic Stenosis Journal of the American College of Cardiology · Taniguchi T et al. | Oct 22 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 20 | Familial Hypercholesterolemia Journal of the American College of Cardiology · Brandts J et al. | Oct 25 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 21 | Sotatercept in Pulmonary Arterial Hypertension Journal of the American College of Cardiology · Reddy Y et al. | Mar 1 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 22 | Management of Mechanical Prosthetic Heart Valve Thrombosis Journal of the American College of Cardiology · Jiménez C et al. | May 1 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 23 | Blood Pressure After Changes in Light-to-Moderate Alcohol Consumption in Women and Men Journal of the American College of Cardiology · Suzuki T et al. | Oct 22 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 24 | Durable Mechanical Circulatory Support Journal of the American College of Cardiology · Tedford R et al. | Sep 25 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 25 | Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism New England Journal of Medicine · Rosenfield K et al. | Mar 28 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 26 | Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease New England Journal of Medicine · Lee Y et al. | Mar 28 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 27 | IVUS-Guided versus Angiography-Guided PCI in Unprotected Left Main Coronary Disease New England Journal of Medicine · Testa L et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 28 | Intravascular Ultrasound–Guided or Angiography-Guided Complex High-Risk PCI New England Journal of Medicine · Diletti R et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 29 | Pathophysiology and management of right heart ischemia Journal of the American College of Cardiology · Goldstein J et al. | Sep 1 | | Yes (JACC) | — | — | — | — |
| 30 | Outcomes for Children With Congenital Heart Disease Undergoing Ventricular Assist Device Implantation Journal of the American College of Cardiology · Amdani S et al. | Jan 8 | | Yes (JACC) | — | — | — | — |
| 31 | Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women—2011 Update Journal of the American College of Cardiology · Mosca L et al. | Mar 1 | — | Yes (JACC) | 7 | — | — | — |
| 32 | The association between physical activity and risk of mortality is modulated by grip strength and cardiorespiratory fitness: evidence from 498 135 UK-Biobank participants European Heart Journal · Celis‐Morales C et al. | Jul 6 | | Yes (European Heart Journal) | — | — | — | — |
| 33 | Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients European Heart Journal · Desai A et al. | May 28 | | Yes (European Heart Journal) | — | — | — | — |
| 34 | Incremental Prognostic Value of Subendocardial Myocardial Flow Reserve in Patients With Normal Perfusion Circulation · Lopez D et al. | Jun 4 | — | Yes (Circulation) | — | — | — | — |
| 35 | Hypertension control: a South Korean success story The Lancet · McLellan F et al. | Jun 1 | — | Yes (The Lancet) | — | — | — | — |
| 36 | FLOWing Toward Holistic Care Journal of the American College of Cardiology · Rangaswami J et al. | Jun 1 | — | Yes (ACC Journal Scan) | — | — | — | — |
| 37 | Performance of Local Large Language Models for Adjudicating Heart Failure Hospitalizations Circulation · Aggarwal R et al. | Jun 1 | — | Yes (Circulation) | — | — | — | — |
| 38 | Response by Omland et al to Letter Regarding Article, “Sacubitril/Valsartan and Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy: The PRADA II Randomized Clinical Trial” Circulation · Omland T et al. | Jun 1 | — | Yes (Circulation) | — | — | — | — |
| 39 | Letter by Jiang et al Regarding Article, “Sacubitril/Valsartan and Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy: The PRADA II Randomized Clinical Trial” Circulation · Jiang B et al. | Jun 1 | — | Yes (Circulation) | — | — | — | — |
| 40 | Letter by Qin et al Regarding Article “Dapagliflozin in Patients Hospitalized for Heart Failure: Primary Results of the DAPA ACT HF-TIMI 68 Randomized Clinical Trial and Meta-Analysis of Sodium-Glucose Cotransporter-2 Inhibitors in Patients Hospitalized for Heart Failure” Circulation · Qin Z et al. | Jun 1 | — | Yes (Circulation) | — | — | — | — |
| 41 | Should Coronary CT Angiography or Coronary Artery Calcium Testing Be Used to Guide Primary Prevention? Circulation · Blankstein R et al. | Jun 1 | — | Yes (Circulation) | — | — | — | — |
| 42 | Standardized End Point Definitions for Clinical Trials in Thoracic Aortic Repair: A Consensus Report From the ARCH–Academic Research Consortium Circulation · Beck A et al. | Jun 1 | — | Yes (Circulation) | — | — | — | — |
| 43 | Minocycline for acute ischaemic stroke: limitations of the EMPHASIS trial – Authors’ reply The Lancet · (444605) L et al. | Jun 1 | — | Yes (The Lancet) | — | — | — | — |
| 44 | Minocycline for acute ischaemic stroke: limitations of the EMPHASIS trial The Lancet · Ghozy S et al. | Jun 1 | — | Yes (The Lancet) | — | — | — | — |
| 45 | Familial hypercholesterolaemia in children and adolescents: a European Atherosclerosis Society consensus statement European Heart Journal · Wiegman A et al. | May 4 | | Yes (European Heart Journal) | — | — | — | — |
| 46 | Real-time MRI-guided right heart catheterization in adults using passive catheters European Heart Journal · Ratnayaka K et al. | Aug 1 | — | Yes (European Heart Journal) | 5 | — | — | — |
| 47 | Lipoprotein(a) as a Potential Causal Genetic Risk Factor of Cardiovascular Disease Journal of the American College of Cardiology · Tsimikas S et al. | Aug 1 | — | Yes (JACC) | 5 | — | — | — |
| 48 | A Genome-First Study of Familial Hypercholesterolemia Comparing African and European Ancestry Individuals Circulation · Winters A et al. | May 29 | — | Yes (Circulation) | — | — | — | — |
| 49 | Transcatheter or Surgical Aortic-Valve Replacement at 7 Years New England Journal of Medicine | May 27 | — | Yes (NEJM) | — | — | — | — |
| 50 | Polypharmacy in Older Adults Hospitalized for Heart Failure Circulation Heart Failure · Ünlü O et al. | Oct 13 | — | Yes (ACC Journal Scan) | 4 | — | — | — |