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October 17, 2025BMC GastroenterologyOpen Access

Association of cardiometabolic risk burden with gastrointestinal bleeding in aspirin users

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Authors

YWYajing WeiJYJiamin YanZGZiting Gao

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Overview

Cohort study shows increased gastrointestinal bleeding risk in aspirin users with cardiometabolic disorders, suggesting need for tailored prevention strategies.

Key Points

  • Aspirin users with higher cardiometabolic risk experienced significantly elevated gastrointestinal bleeding.
  • The incidence rate of GI bleeding increased from 4.53 to 9.64 per 1000 person-years with more cardiometabolic risk factors.
  • Diabetes and hypertension were associated with greater GI bleeding risk, indicating a need for preventative measures.
  • Stratified analysis suggested stronger associations in individuals with a history of gastrointestinal disorders.

Cite This Study

Wei et al. (2025) studied this question.

synapsesocial.com/papers/68f25c913dc7eb0776cbc0fehttps://doi.org/10.1186/s12876-025-04347-3
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