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February 22, 2016JAMA28,810 citationsOpen Access

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

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MSMervyn SingerBury CollegeCDClifford S. DeutschmanNorthwestern UniversityCSChristopher W. SeymourUniversity of Pittsburgh

Key Points

  • To establish updated definitions and clinical criteria for sepsis and septic shock, aiming for better management and research uniformity.
  • Developed new definitions for sepsis and septic shock based on expert consensus.
  • Emphasized the need for definitions to facilitate timely management and recognition in clinical settings.
  • The updated definitions provide more consistent criteria for epidemiologic studies.
  • They aim to enhance early recognition and prompt intervention for patients at risk of sepsis.

Abstract

These updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsis or at risk of developing sepsis.

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Cite This Study

Singer et al. (2016) studied this question.

synapsesocial.com/papers/696fa532b84853cc293d8002https://doi.org/10.1001/jama.2016.0287
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