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January 25, 2026The Annual Review of Pharmacology and Toxicology1 citationsOpen Access

Treating Pregnant and Lactating Women: Insights from Clinical Pharmacology

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Authors

DODavies OtienoFOFrancis Williams OjaraNRNaomi Richardson

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Overview

Observational insights improve drug safety and efficacy in pregnant and lactating women, suggesting better pharmacotherapy approaches.

Key Points

  • The aim is to address the lack of clinical trial data on drug pharmacokinetics in pregnant and lactating women.
  • Review of ethical and regulatory shifts related to trial inclusion.
  • Analysis of pharmacological modeling techniques for trial design.
  • Integration of various research data to assess physiological changes.
  • Legislative changes have improved research inclusion for this demographic.
  • Innovative pharmacokinetic models help optimize drug dosing.
  • Emerging technologies offer new insights into maternal and infant drug exposure.

Cite This Study

Otieno et al. (2026) studied this question.

synapsesocial.com/papers/6975b1cefeba4585c2d6d43ehttps://doi.org/10.1146/annurev-pharmtox-071724-014725
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