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March 3, 2026
Open Access
Use of medications with pharmacogenomic guidelines and adverse outcomes in hospitalised older patients: a retrospective cross-sectional study
VD
Victoria David
University of Bradford
CM
Ciarán D. McInerney
University of Sheffield
JT
Justine Tomlinson
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Puntos clave
Adverse outcomes are significantly associated with medications not guided by pharmacogenomic guidelines, highlighting risks.
In the analysis, 75% of adverse outcomes occurred in cases where pharmacogenomic guidelines were overlooked.
Retrospective cross-sectional analysis compared prescriptions to pharmacogenomic guidelines among older hospitalized patients.
Findings emphasize the need for integrating pharmacogenomic guidelines to lessen medication-related risks in older adults.
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David et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75aafc6e9836116a20d4e
https://doi.org/https://doi.org/10.1038/s41397-026-00396-3
Use of medications with pharmacogenomic guidelines and adverse outcomes in hospitalised older patients: a retrospective cross-sectional study | Synapse