GCSH promotes colorectal cancer progression by inhibiting Cuproptosis through the PI3K/AKT-FDX1 axis

Puntos clave

• Colorectal cancer progression is enhanced by GCSH's inhibition of cuproptosis, impeding cell death.
• GCSH's impact was correlated with changes in fdx1 expression, showing significant molecular interactions.
• Assessment using molecular pathway analysis highlighted the role of the PI3K/AKT axis in cancer advancement.
• Findings may enable new therapeutic strategies targeting GCSH to combat colorectal cancer.