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March 3, 2026
Open Access
The efficacy analysis of immunotherapy rechallenge after progression from first-line chemo-immunotherapy in advanced non-small cell lung cancer
WS
Wenhao Shi
RK
Rui Kong
JX
Jin Xiong
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Puntos clave
Immunotherapy rechallenge may maintain efficacy after progression from first-line chemo-immunotherapy in advanced non-small cell lung cancer.
Evidence shows promising outcomes with better disease control compared to traditional approaches.
Analysis included patients who experienced initial progression but later responded to rechallenge with immunotherapy.
May enable new treatment pathways for patients failing first-line chemo-immunotherapy, though further validation is needed.
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Shi et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b4ec6e9836116a22688
https://doi.org/https://doi.org/10.1186/s12865-026-00800-4
The efficacy analysis of immunotherapy rechallenge after progression from first-line chemo-immunotherapy in advanced non-small cell lung cancer | Synapse